General Cell Lines and Cell Cultures
ATCC Desulfovibrio vulgaris; subsp. vulgaris; genomic DNA
Genomic DNA isolated from Desulfovibrio vulgaris subsp. vulgaris strain NCIB 8303 [DSM 644; Hildenborough]. This bacterial strain is also available as ATCC® Catalog No. 29579™.
ATCC Moraxella catarrhalis; Strain 61240
Moraxella catarrhalis strain 61240 was isolated in 2005 in Canada. This strain is part of the national surveillance study called CROSS (Canadian Respiratory Organism Susceptibility Study).
ATCC Merck Pneumococcal polysaccharide powder Type 8 (d8) 200mg
Purified pneumococcal polysaccharides are manufactured by Merck & Company for small quantity distribution by ATCC. The pneumococcal powders include those types which are components of the current 23-valent vaccine against Streptococcus pneumoniae.Each of the polysaccharide antigens used in the polyvalent vaccine is extracted and purified separately. These vaccine products can be used to assay for type-specific antibodies, research immune responses and study immunodeficiencies.
ATCC Peptostreptococcus anaerobius; genomic DNA
Genomic DNA isolated from Peptostreptococcus anaerobius strain MSHD. This bacterial strain is also available as ATCC Catalog No. 49031™.
Lonza Walkersville Rat Brain Cortex Astrocytes
Ready-to-use Clonetics Rat Brain Cortex Astrocytes are obtained from rat brain passaged once and prepared as cell suspensions for shipment on dry ice Each vial contains approximately 1 million cells Astrocytes can be easily thawed and cultured Astrocytes can be harvested and re-plated or stored frozen for later use The cells are shipped overnight Recommended medium AGM BulletKit (CC-3186)
ACROBiosystems HEK293/Human LDL R Stable Cell Line
Low-Density Lipoprotein (LDL) Receptor is also known as LDLR, FH, FHC, LDLCQ2, and is a mosaic protein of ~840 amino acids (after removal of signal peptide) that mediates the endocytosis of cholesterol-rich LDL. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. The receptor also recognizes the apoE protein found in chylomicron remnants and VLDL remnants (IDL). It belongs to the Low density lipoprotein receptor gene family. LDL receptor complexes are present in clathrin-coated pits (or buds) on the cell surface, which when bound to LDL-cholesterol via adaptin, are pinched off to form clathrin-coated vesicles inside the cell. This allows LDL-cholesterol to be bound and internalized in a process known as endocytosis and prevents the LDL just diffusing around the membrane surface. This occurs in all nucleated cells (not erythrocytes), but mainly in the liver which removes ~70% of LDL from the circulation.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Brain: Hippocampus, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Eurofins Discoverx PathHunter U2OS PD-L1/PD-L1 Dimerization Cell Line, 2 vials. (93-1129C3)
The PathHunter PD-L1/PD-L1 Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. anti PD-L1 antibody) induced dimerization of PD-L1/PD-L1 receptors. This product uses EFC technology. The cell line included overexpresses PD-L1 target protein fused to PK alongside PD-L1 target protein fused to EA. Upon ligand-induced dimerization of PD-L1/PD-L1, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/checkpoint.
ATCC Listeria monocytogenes; Strain Li 23; genomic DNA
Genomic DNA isolated from Listeria monocytogenes Strain Li23. This bacterial strain is also available as ATCC Catalog No. 19114™.
Biochain Institute Inc Paraffin Tissue Section - Parkinson's Disease: Brain, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Biochain Institute Inc Matched Pair - DNA - Human Primary and Metastatic Tumor Tissue: Colon, 2x10 ug/PK
BioChain's human DNA matched pair products include: Primary Pair (PP), Primary and Metastasis Pair (PM). PP consists of DNA prepared from primary tumor and its adjacent normal tissue; PM consists of DNA prepared from primary tumor and corresponding ponding metastatic tumor. Genomic DNA in each pair is prepared from the same donor. This product line is designed foridentifying tumor-specific genes and tumor metastatic genes.
ATCC RAW 264.7 gamma NO (-); Macrophage; Mouse (Mus musculus)
RAW 264.7 gamma NO(-) was derived from the RAW 264.7 (see ATCC TIB-71) mouse monocyte/macrophage cell line Unlike the parental line, RAW 264.7 gamma NO(-) does not produce nitric oxide upon treatment with interferon gamma alone, but requires LPS for full activation (the iNOS promoter linked to a luciferase reporter gene is also unresponsive to IFN- alone). This cell line was deposited by SW Russell and can be used in assay development.
ATCC Merck Pneumococcal polysaccharide powder Type 20 (d20) 2mg
Purified pneumococcal polysaccharides are manufactured by Merck & Company for small-quantity distribution by ATCC. The pneumococcal powders include those types which are components of the current 23-valent vaccine against Streptococcus pneumoniae. Each of the polysaccharide antigens used in the polyvalent vaccine is extracted and purified separately. These vaccine products can be used to assay for type-specific antibodies, research immune responses and study immunodeficiencies.
Eurofins Discoverx Ready-to-Assay MRGPRX1 Receptor Frozen Cells, 2 Vials of Cells. (HTS122RTA)
The Ready-to-Assay MRGPRX1 Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. BAM22) based activation of MRGPRX1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses MRGPRX1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of MRGPRX1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC Enterobacter cloacae; subsp. dissolvens; genomic DNA
Genomic DNA isolated from Enterobacter cloacae subsp. dissolvens Strain ICPB ED105. This bacterial strain is also available as ATCC Catalog No. 23373™.